12.09.2020

Cocamidopropyl betaine causes cancer. Cocamidopropyl Betaine in cosmetology


Cocamidopropyl betaine(Cocamidopropyl Betaine) - combined detergent substance.

Description

By appearance is a clear or slightly turbid liquid of light yellow color with a slight characteristic odour. The content of the main substance is 46-48%, sodium chloride 6-7%. Its pH is 4.5-5.5. Its combination with anionic surfactants leads to a significant improvement in the dermatological qualities of the final product.

Application

It is used as an active additive in liquid, pasty, detergents, washing and cleaning products.

It has good foaming and cleaning properties, increases viscosity.

Cocamidopropyl betaine is a very popular ingredient in foaming cosmetic products. feature which is a remarkable ability to clean the hair roots and scalp from fat.

Main applications:

  • baby skin cleansers
  • facial cleansing creams and gels,
  • hair conditioners,
  • hair conditioners,
  • shower gels,
  • bath foam,
  • facial cleansing gels and foams,
  • hand soap,
  • cleaning products for children
  • additive in liquid and solid soaps. Improves their properties
  • suitable for use in cleansers, cosmetics, foam cleansers,
  • used as an active additive in liquid, pasty, detergents, washing and cleaning products,
  • has good foaming and cleaning properties, increases viscosity,
  • can be used in compositions that do not contain additional surfactants.

How to use: To prepare the formulation, it is enough to stir the surfactant with water and add the active ingredients. Bath foam: up to 20% Shampoos: 20-30% Conditioners: 10-15% Gels: 20-25%

Properties

mild co-surfactant compatible with anionic/cationic/nonionic surfactants. Auxiliary surfactants include amphoteric, non-ionic and cationic substances. They are necessary in shampoo formulations to increase the compatibility of basic (anionic) surfactants with skin and hair, increase foaming properties, regulate viscosity, and reduce the degreasing effect.

  • Reduces the irritating effect of other surfactants.
  • In combination with anionic surfactants, it becomes a thickener, improves foaming ability and increases the safety of formulations.
  • It has good cleaning and foaming properties.
  • It has the properties of a conditioner and antistatic for hair.
  • Used in bio-cosmetics.
  • Provides pleasant cleansing, foaming good care for hair and skin.
  • Compatible with all types of surfactants (surfactants), can be used as the main surfactant.
  • foam stabilizer.
  • Its combination with anionic surfactants leads to a significant improvement in the dermatological qualities of the final product.
  • Production method: obtained from coconut oil (a derivative of cocamide and glycine betaine), recently babassu-amidopropyl betaine has also been produced - from babassu oil close in composition to coconut oil.
  • Kok-amidopropyl betaine and babassu-amidopropyl betaine are interchangeable and almost identical in application.

Impact on a person

It has been claimed to cause an allergic reaction in some users, but controlled experimental studies have found that these cases may represent irritants rather than true allergic reactions. In addition, research results have shown that CAPB has low potential if amidoamine (AA) and dimethylaminopropylamine (DMAPA) impurities are kept low and controlled. Other studies have concluded that allergic reactions to CAPB are most evident, most likely due to amidoamine. Cocamidopropyl Betaine was voted low allergenic by the American Contact Dermatitis Society in 2004.

Precautionary measures

  • Not a hazardous product, normal handling as for industrial chemicals.
  • Wash hands with water after work.
  • In case of contact with eyes, rinse thoroughly with warm water. In case of contact with skin, rinse thoroughly with plenty of water.

Additionally

In the laboratory of Experimental Dermatology of the University of Cadiz (Spain), it was demonstrated in experiments that, in order of increasing irritant effect on the skin, the most well-known surfactants are arranged as follows.


To reduce the negative impact of tensides, polyelectrolytes are included in the composition of cosmetics: sorbitol, protein hydrolysates, glycerin, and so on.

What is the damage to the skin?

Like any chemical component, cocamidopropyl betaine can cause local irritation of the skin, manifested in peeling, rashes and redness. But such reactions are extremely rare, most often in those whose body does not perceive this component. Most people use cosmetic and hygiene products containing this substance without any problems.

Cocamidopropyl betaine is irritating to the organ of vision. In case of penetration into the eyes, it is necessary to wash abundantly with running, cold water, until the tearing of the eyes and burning sensation stop. All cosmetical tools it is necessary to use strictly for its intended purpose, when taken orally, cocamidopropyl betaine is quite toxic.

Expert opinions

At the moment, there is no consensus among experts regarding the safety of cocamidopropyl betaine. The substance, if swallowed, can cause significant harm. The lethal dosage for rats is 5 grams. per 1 kg of body weight. Some experts insist that PAS negatively affects the thyroid gland and liver, but no special studies have been conducted.

The US FDA has recognized cocamidopropyl betaine as a safe substance, taking into account its use as a cosmetic and hygiene product. However, creams that are applied for a long time and involve penetration into subcutaneous tissue are not safe and can do more harm than good. So you can use shampoos, shower gels with this component, but if you meet it in face masks, do not try to use such a tool.

Benefits of Cocamidopropyl Betaine

  • It is characterized by excellent foaming and cleansing properties.
  • Absorbs the irritating effect of other surfactants.
  • Has antistatic properties.
  • Can be used as the main surfactant.
  • Can be combined with all types of surfactants.
  • Provides high-quality cleansing and foaming, which guarantees thorough care for the skin and hair.
  • It is a foam stabilizer.
  • When combined with anionic surfactants, it significantly improves the dermatological properties of cosmetics.

Applications of Cocamidopropyl Betaine in Cosmetics


Cocamidopropyl betaine is one of the most gentle and safe surfactants, it is used in bio-cosmetics. It has an antistatic and conditioning effect on the hair, facilitates combing dry and damaged hair, provides high-quality skin care, and gives pleasant cleansing and foaming. It is also often used in the manufacture of makeup removers. The component is found in almost all hygiene products.

  • Cream shower gels
  • Foaming bath liquids
  • Balms, conditioners, hair sprays
  • Hygiene products for children
  • Powders, rinses, pastes and gels for oral care
  • Tonics and lotions
  • Makeup removers (foams, gels, milk)
Cocamidopropyl betaine is added to Herbal Essences shampoos, is also included in Siberica bio-cosmetics, and is used in Parodontax toothpaste.

In cosmetology, Cocamidopropyl betaine is now used by many manufacturers. In principle, this component is gentle compared to other chemical compounds, and its danger and harm to the body, if used correctly, is minimal. But still, it would be better to add a harmless surfactant instead.

natural betaine

INCI: betaine

Externalview: white crystals Solubility:soluble in water
Features of input into the recipe: dissolves easily in warm water 20-30°C) while stirring. It is recommended to introduce into the formulation in the form of an aqueous solution in an already formed emulsion, at temperatures up to 40 ° C .
Recommended dosage: 2 - 10% (usually up to 4%)

Storage conditions:

store in a cool place in a closed container. Due to its hygroscopicity, betaine should be stored in a dry place..

Description
Betaineor trimethyl glycine is a very simple, common molecule found in nature.It is found in plants and animals, especially crustaceans. natural betaine- pure, purified raw material obtained from sugar beet juice. It belongs to the class of amino acids.Due to its structure, betaine can easily form hydrogen bonds with water and other molecules, has multifunctional properties and in particular helps to solubilize some other molecules. It is non-toxic LD 50 is 11.2 g/kg) and is used as a food additive; soluble in water and chemically stable. It has been studied that betaine is secreted in marine microorganisms in order to resist osmotic stress.
Betaine has a wide range of cosmetic properties, the main of which are active moisturizing (hygroscopic), conditioning and reducing the irritating effect of surfactants.


What is the difference between natural and synthetic betaines?

· Synthetic betaines are used as surfactants.

· Unlike synthetic betaines, natural betaine is osmolyte, a true water carrier that controls water balance and protects cells from osmotic stress.

· Therefore, the functions of natural and synthetic betaines are very different.

The benefits of natural betaine in personal care formulations were discovered 30 years ago and have since
Since betaine is widely used due to its unique properties and ease of use in formulations.

Properties

Betaine in skin care

· True humectant, controls the water balance in the skin

· Strengthens the skin barrier

· Promotes firmness and elasticity of the skin

· Gives the skin smoothness, evenness, softness, improves appearance

· Anti-aging action

· Reduces chemical and mechanical irritation

· Anti-inflammatory effect

· Brightening action

· Reduces stickiness

· Reduces the irritating effect of surfactants

True moisturizer– water balance control

Natural betaine is an organic osmolyte that attracts moisture. Protects cellular macromolecules from external influences. Maintains the water balance of cells, cells can accumulate and release betaine.

Strengthens skin barrier - effect on the skin

The penetration of betaine through the stratum corneum is comparable to other osmolytes.
Betaine can be taken up by keratinocytes via specific transporters to restore water balance after dehydration or UV radiation. Betaine can improve the firmness of the tight junction and thus prevent water loss from the skin and penetration of harmful substances into the skin.

Betaine increases the elasticity of tight junctions in epidermal keratinocytes

Betaine improves the elasticity of tight joints ( tight junctions) and contributes to the improvement of the condition inside - outside skin barrier and skin hydration status.
Tight connections do their part to prevent the penetration of harmful substances such as allergens, pollutants, etc. into the skin, as well as in preventing water loss.

Anti-inflammatory action

Betaine reduces chemical and mechanical irritation.

· Mechanical irritation

Betaine has good anti-inflammatory effect . Evaluation of the anti-inflammatory effect of betaine in vivo, Dermscan 1996.
In studies conducted by the manufacturer, a 4% aqueous solution of betaine was compared with distilled water and untreated areas for the prevention and reduction of erythema formed by mechanical damage to the skin.
The results show a very significant reduction in erythema after 60 minutes of application. This proves that betaine has a good anti-inflammatory effect on superficial inflammatory lesions. Using this property, a remedy for prickly heat was patented.

· Chemical irritation:

Betaine protects against chemical irritation.
The effect on the skin of Natural betaine in combination with surfactants was tested by the RBC Test. Two mixtures of harsh and skin irritating surfactants were tested according to the RBC test, with and without the addition of Natural Betaine. Natural betaine was added at a concentration of 3.5%.
Conclusions: Natural betaine significantly improved the softness of both formulations. The mildness rating of surfactants has been changed from "irritant" to "moderately irritating".

Anti-aging action

In a study conducted in vitro, est. the effect of betaine (1%) onfibroblast culture, the results showed an increase in proliferation rates of 56.4% and 41.5% compared to the control sample after 24 h and 48 h. At the same time, the level of hydroxyproline increased depending on time and was higher than the control sample after three weeks ( 13.5vs. 9.3 mg/dish ) and four weeks ( 16.9vs. 12.3 mg/dish ). The exact mechanism of this action, as yet unexplained, remains uncertain; but it opens up new possibilities for using betaine in anti-wrinkle products.One of the possibilitiesThis action is that betaine is involved in the protection of cells from oxidative stress through the so-called "osmolytic strategy".
Another possibility is that betaine functions as a methyl group donor, increasing the ability of membrane lipids to move from phosphatidylethanolamine ( PE ) to phosphatidylcholine ( PC ) , the so-called flip-flop mechanism. PC releases its methyl groups inside the cell, then becoming PE returns to the outer cell wall to receive a supply of methyl from methyl donors. This "flip-flop" mechanism increases fluidity cell membrane, facilitating the absorption of nutrients in the cell ( Kampf et al.)

Brightening action

In a recent study conducted by the manufacturer, a lotion containing 4% betaine was evaluated for skin whitening activity. The test was conducted in Thailand with 22 dark-skinned participants. Skin color measurement was taken with Chromameter Minolta CR 321 as well as digital photos. results showed significant skin lightening:

· Significant increase L * parameter in 64%, 82% and 73% of test participants, respectively, i.e. significant brightening effect of hyperpigmented spots;

· Significant increase I.T.A. ° on days 28 (+ 51%), 56 days (+ 99%) and 84 days (+ 100%) in 73%, 86% and 77% of participants;

· Significant decrease in b * on day 84 68% of participants, i.e. reduction of yellow pigment in skin color.

These results open up new possibilities for using betaine in combination with other ingredients in whitening products. Betaine brightens dark spots due to its anti-inflammatory effect, preventing the melanocyte stimulation pathway.

Home " Hair loss " Surfactants and surfactants - harm or benefit? Cocamidopropyl Betaine in cosmetology. What harm does it bring to health

Cosmetic products today have a large number of chemical components in their composition. Buyers often see a substance such as Cocamidopropyl Betaine on the ingredient list. It is necessary to understand what it is and whether it is harmful to health and beauty.

Description

This is a substance that manufacturers obtain from palmitic or other fatty acids. Cocamidopropyl betaine is a white or yellow mass found in many shampoos, shower gels and toothpastes. This component can perform the functions of alkalis or acids, depending on the conditions. Its pH is 4.5-5.5, and the acid-base balance of human skin is from 3.5 to 5.9.

The component is a surfactant, i.e. it can accumulate on the surface. When choosing cosmetics, many people try to choose products that do not contain Cocamidopropyl Betaine. This is because not everyone is aware of its action and possible detrimental effects on health and beauty.

Properties

This is a component that combines well with other surfactants in the composition of cosmetic products. The use of Cocamidopropyl Betaine in the production of cosmetics is necessary to perform the following tasks:

  • Formation of persistent foam and effective cleaning of surfaces.
  • It has hair conditioning properties and acts as an antistatic agent.
  • Gentle cleansing of the skin and hair from dirt and grease.
  • Improvement of the dermatological properties of the product in combination with anionic surfactants.

Recently, Cocamidopropyl Betaine has been obtained from coconut oil and the babassu oil, which is close to it in composition. This softens the cleansing properties of the component and its effect on the skin and hair.


Where is it contained?

Manufacturers add this substance as a foaming agent and cleaner to various cosmetic and household products. Cocamidopropyl Betaine is found in cosmetics, in liquid, pasty, washing and cleaning products.

It is the most popular in cosmetics, among other cleansing ingredients, because its characteristic feature is the ability to cleanse the hair and scalp without harming them. Cocamidopropyl Betaine can be found in shampoo, conditioner, shower gel, liquid soap, facial cleansers, toothpaste, bath foam, baby hygiene products, etc.

Permissible content

The allowable amount of Cocamidopropyl Betaine in the composition of cosmetic products depends on the amount of other surfactants included in it. Most often, such a component can be found as a secondary surfactant, and its content rate is as follows:

  1. Shampoo - 5-35%.
  2. Conditioner and hair balm - 5-15%.
  3. Toothpaste - 1-3 %.
  4. Shower gel and soap - 5-15%.

These indicators are set by the competent authorities to ensure that this chemical does not harm human health during use. To mitigate the harmful effects of surfactants, manufacturers add a large number of components to cosmetics that reduce the negative effects of Cocamidopropyl Betaine.


Role in cosmetic products

Many people are confused about what surfactants are for in cosmetics and household products. Recently, a similar substance has been added to bio-cosmetics in combination with various components that can improve its effect.

Cocamidopropyl Betaine - what is it in shampoo? In hair shampoos, this substance is responsible for persistent foaming, which allows you to gently and effectively cleanse the hair and scalp from impurities. In the presence of abundant foam during shampooing, there is no strong physical effect on the hair. This eliminates the detrimental effect on their condition.

Both in shampoo and in other cleansing cosmetic products, it is necessary for high-quality cleansing of the skin from impurities. Foam, which is formed with Cocamidopropyl Betaine, perfectly cleans the surface of the skin or teeth from dirt.


Detrimental impact

Any chemical substance can adversely affect the health and beauty of a person if it deviates from the permissible content standards in the composition of the product or if the products are used improperly. Manufacturers who care about their reputation and the quality of their products do not allow exceeding the permissible limits in the compositions.

Most often, the harm of Cocamidopropyl Betaine is a slight redness and irritation on the skin of the body and head. This occurs as a result of prolonged exposure of the foam to the surface of the skin. Redness and irritation are accompanied by rash and itching. A similar reaction, in most cases, occurs in people with hypersensitivity to chemicals or with sensitive skin.

Cocamidopropyl betaine is harmful to the organs of vision and mucous membranes. In case of contact with the eyes of a cosmetic product that contains a similar component, it is necessary to immediately rinse the eyes with cool clean water until the burning sensation completely stops. It is important to ensure that the substance does not enter the body because in this case it becomes very toxic.

Positive properties

Due to the many positive qualities, Cocamidopropyl Betaine is included in the list of ingredients in cosmetic products. It is one of the safest and most gentle surfactants and is widely used in hair, body and dental care products.

A similar component can be found in washing and shower gels, as it forms a foam that effectively and gently cleanses the skin of impurities. Cocamidopropyl Betaine does not clog pores or cause irritation in people with normal skin types.

In conditioners and hair balms, it has an antistatic effect. It can often be found in micellar water, which is a guarantee of thorough facial skin care.

Cocamidopropyl Betaine in toothpaste is responsible for cleaning teeth from plaque and protecting against caries, as well as persistent foaming, which helps to kill bacteria and keep the mouth fresh. Thanks to this substance, an oral cleanser was launched on the market for patients who wear fixed structures on their teeth. Cocamidopropyl is the basis of a liquid product that, when sprayed into the mouth, forms a cleansing foam and is easily rinsed off with water.

The substance does an excellent job of removing makeup from the face, which gives it the right to be part of various cosmetic products. It is able to dissolve even the most waterproof makeup, and is included in the list of ingredients of micellar water, tonic and makeup remover milk.


Conclusion

When compared to other surfactant chemicals, Cocamidopropyl Betaine is the safest and most gentle. It can cause irritation, itching, rashes and discomfort in people with sensitive skin types.

In most cases, the substance effectively cleanses the skin and hair of impurities without adverse effects. Other surfactants cause more significant harm not only to beauty, but also to human health. When choosing products containing Cocamidopropyl Betaine, customers are confident that such a cosmetic product will be gentle and effective on skin, hair and teeth.

Other designations: coco betaine, cocamidopropyl. amidopropyl betaine.

Reference

Cocamidopropyl betaine is a liquid mass that is obtained from the fatty acids of coconut oil. Forms simpler substances - cocamide and glycine betaine. Being an amphoteric substance, cocamidopropyl betaine acts as an acid or alkali under different conditions.

The color of cocamidopropyl betaine is white to yellow. The smell is almost imperceptible.

It is a surface-active substance (surfactant). It is used in cosmetics as a mild cleaner, often along with sodium lauryl sulfate and other more powerful surfactants.

As part of hair care products, it prevents the formation of a static electric charge.

Being a component of cosmetics for skin and hair, cocamidopropyl betaine helps to reduce the irritating effect of other surfactants.

This substance is also used in dentistry. Cocamidopropyl betaine is used as an ingredient in toothpastes and powdered products. It can also be a component of special liquid substances that are designed to care for the oral cavity for people with baguettes and other non-removable structures on their teeth.

Cocamidopropyl betaine is actively used for the production of a wide variety of skin and hair products. Its action is aimed not only at ensuring the proper cosmetic effect, but also at improving a number of characteristics of the composition of a particular emulsion:

  • is a skin and hair cleanser;
  • helps to prevent the occurrence of static electric charge on the hair;
  • used for skin and hair conditioning;
  • provides easier combing of hair;
  • has excellent foaming properties;
  • helps maintain foam stability even in hard water conditions;
  • used as an emulsifier;
  • makes liquid emulsions thicker (thickener).

Cocamidopropyl betaine is a common component of the composition of the following products:

  • liquid and solid soap;
  • cleansing children's cosmetics;
  • creams, lotions and gels for facial skin;
  • shampoos, balms and hair conditioners,
  • bath products (shower gels; foams);
  • toothpastes and powders;
  • balms for cleansing the mouth.

Cocamidopropyl betaine is also used as the main or auxiliary surfactant.

Cocamidopropyl betaine can be an active additive in detergents, cleaners, washing (liquid and pasty) products.

Cocamidopropyl betaine is a non-toxic component, but in rare cases it can provoke an allergic reaction.

Has restrictions on use in cosmetics.

Attention: may irritate the mucous membrane of the eyes: if the substance gets into the eyes, rinse them with water (for twenty minutes).


In the compositions of shampoos, shower gels, toothpastes, the Cocamidopropyl betaine component is often found. It is a liquid mass of white or yellowish color, which is obtained from fatty acids (palmitic, lauric and others) of coconut oil. As a result, a combination of simple substances is formed - cocamide and glycine betaine. Depending on the conditions, Cocamidopropyl betaine can act as both an alkali and an acid. Let's find out if this component in cosmetic products is dangerous or safe.

Characteristics of Cocamidopropyl Betaine

  • Color: white or yellow
  • Smell: practically absent
  • Acidity: in 10% - 6
  • PH: 4.5 to 5.5;
  • Amphoteric, so it can act as both a base and an acid
  • Surfactant (surfactant) - accumulates on the surface and lowers surface tension;
  • Works well with various surfactants
  • Shampoo (with alkyl polyglycosides and anionic) 5-30%
  • Toothpaste up to 2%
  • In the form of a foaming agent for gels and soaps - 5-10%
  • Conditioners and hair balms - 10-15%

To reduce the negative impact of tensides, polyelectrolytes are included in the composition of cosmetics: sorbitol, protein hydrolysates, glycerin, and so on.

What is the damage to the skin?

Like any chemical component, cocamidopropyl betaine can cause local irritation of the skin, manifested in peeling, rashes and redness. But such reactions are extremely rare, most often in those whose body does not perceive this component. Most people use cosmetic and hygiene products containing this substance without any problems.

Cocamidopropyl betaine is irritating to the organ of vision. In case of penetration into the eyes, it is necessary to wash abundantly with running, cold water, until the tearing of the eyes and burning sensation stop. All cosmetics must be used strictly for their intended purpose, when taken orally, cocamidopropyl betaine is quite toxic.

Expert opinions

At the moment, there is no consensus among experts regarding the safety of cocamidopropyl betaine. The substance, if swallowed, can cause significant harm. The lethal dosage for rats is 5 grams. per 1 kg of body weight. Some experts insist that PAS negatively affects the thyroid gland and liver, but no special studies have been conducted.

The US FDA has recognized cocamidopropyl betaine as a safe substance, taking into account its use as a cosmetic and hygiene product. However, creams that are applied for a long time and involve penetration into the subcutaneous tissue are not safe and can do more harm than good. So you can use shampoos, shower gels with this component, but if you meet it in face masks, do not try to use such a tool.

Benefits of Cocamidopropyl Betaine

  • It is characterized by excellent foaming and cleansing properties.
  • Absorbs the irritating effect of other surfactants.
  • Has antistatic properties.
  • Can be used as the main surfactant.
  • Can be combined with all types of surfactants.
  • Provides high-quality cleansing and foaming, which guarantees thorough care for the skin and hair.
  • It is a foam stabilizer.
  • When combined with anionic surfactants, it significantly improves the dermatological properties of cosmetics.

Applications of Cocamidopropyl Betaine in Cosmetics

Cocamidopropyl betaine is one of the most gentle and safe surfactants, it is used in bio-cosmetics. It has an antistatic and conditioning effect on the hair, facilitates combing dry and damaged hair, provides high-quality skin care, and gives pleasant cleansing and foaming. It is also often used in the manufacture of makeup removers. The component is found in almost all hygiene products.

  • Cream shower gels
  • Foaming bath liquids
  • Balms, conditioners, hair sprays
  • Hygiene products for children
  • Powders, rinses, pastes and gels for oral care
  • Tonics and lotions
  • Makeup removers (foams, gels, milk)

Cocamidopropyl betaine is added to Herbal Essences shampoos, is also included in Siberica bio-cosmetics, and is used in Parodontax toothpaste.

In cosmetology, Cocamidopropyl betaine is now used by many manufacturers. In principle, this component is gentle compared to other chemical compounds, and its danger and harm to the body, if used correctly, is minimal. But still, it would be better to add a harmless surfactant instead.